By: CA Staff Writer | August 1, 2025
Clarksdale, Mississippi – Red Panther Brewing Co. is making waves in Clarksdale, Mississippi, blending rich local heritage with finely crafted beer. Located at 121 Delta Avenue, this dynamic brewery opened its doors in 2023 and has quickly become a must-visit for both locals and visitors looking for something fresh, flavorful, and distinctly Delta.
The name “Red Panther” pays tribute to the area’s Choctaw roots—kowi homma, meaning “red panther”—and that deep cultural pride runs through every pint. With a lineup that ranges from crisp and classic to boldly experimental, Red Panther Brewing Co. offers something for every beer enthusiast. Fan favorites include the Delta Kolsch, Clarksd’Ale, and the refreshing Pomegranate Sour, alongside rotating seasonal options like Lemon Ginger Shandy and Mexissippi Lager. For those seeking non-alcoholic options, their house-made ginger and root beers are crowd-pleasers.
Step inside the welcoming taproom and you’ll find a laid-back space that’s perfect for catching up with friends, enjoying live music, or chatting with the knowledgeable staff. The brewery is open Wednesday through Saturday from 4 PM to 8 PM and Sunday from 3 PM to 7 PM.
Beyond the taproom, Red Panther Brewing Co. is steadily expanding its reach. Their brews are now available in over 60 bars, restaurants, and stores across Northern Mississippi—bringing a taste of Clarksdale to communities far and wide.
Whether you’re a craft beer connoisseur or just looking to support a local business with a powerful story, Red Panther Brewing Co. delivers a uniquely Delta experience that keeps people coming back for more.




Photo Credit: Red Panther Brewing Co
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